Pomyelo 2mg capsule - Pomalidomide | Myapplepharma

Pomyelo 2mg is a product which is endorsed by FDA, containing an active anti-cancer drug called Pomalidomide.
Pomyelo 2mg is available as orally bioavailable thalidomide derivative with various therapeutic activities such as;
Immuno modulatory
Anti-angiogenesis
Anti-neoplastic
Pomyelo 2mg is like thalidomide & Lenalidomide with related to decreased rate of serum aminotransferase elevations during treatment.
This may lead to severe liver injury.
Pomyelo 2mg is involved in the treatment for regression & unmanageable multiple myeloma.
Pomyelo 2mg is used in the patients who are failing to response for Lenalidomide treatment.
Pomyelo 2mg is used in combination with dexamethasone.

INDICATION

The major therapeutic indication of Pomyelo 2mg is involved in the treatment of multiple myeloma.
This treatment is occurred by combining with dexamethasone for reducing the side effect associated with Pomyelo 2mg.
Pomyelo 2mg is majorly indicated in patients who are not reacts for prior two therapies like Lenalidomide & proteasome inhibitor.

DOSAGE & ADMINISTRATION

Pomyelo 2mg should be concomitant with dexamethasone.
Pomyelo 2mg capsules should be taken with or without food.
During hematological toxicities:

Neutropenia:

ANC (absolute neutrophils count) <500/mcl: Postpone the Pomyelo therapy and provide CBC weekly
ANC more than or equal to 500/mcl: Continue the Pomyelo3mg daily.

Thrombocytopenia:

Platelets count <25,000/mcL: postpone the Pomyelo treatment & follow the CBC
>50,000/mcL: continue 3mg of Pomyelo
Pomyelo 2mg with potent CYP1A2 inhibitor:
During this combination reduce the dose of Pomyelo by 50%

WARNING

There are two major worsening condition may occur during the treatment using with Pomyelo 2mg.

Embryo fetal damage:

Pomyelo 2mg capsules are contraindicated to pregnancy period.
During the treatment, patients avoid to becoming pregnant.
Use effective contraceptives for preventing pregnancy during therapy.

WORK AS

Pomyelo 2mg exhibits various activities like;

Immuno modulatory:

Boosted the T-cells & natural killer cell mediate immunity.
The drug is prohibited the formation of pro-inflammatory cytokines by monocytes.

Anti-angiogenesis:

Interfere with formation of new vessels and leads to inhibit the cell division.

SIDE EFFECTS

More common effects :

If taken during pregnancy, Severe life-threatening human birth defects
Fatigue
Weakness
Low white blood cell count
Anemia
Constipation
Nausea